Source:http://linkedlifedata.com/resource/pubmed/id/19481934
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
13
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pubmed:dateCreated |
2009-6-9
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pubmed:abstractText |
The nitroaldol reaction of nitro[(11)C]methane and formaldehyde using EtOH and EtONa efficiently provided 2-nitro[(11)C]ethanol in 3min. The nitro group reduction in the presence of NiCl(2) and NaBH(4) in MeOH followed by purification using semi-preparative HPLC using 10% EtOH aqueous solution as an eluent proved to be a practical and accessible method for the synthesis of 2-amino[2-(11)C]ethanol.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Carbon Isotopes,
http://linkedlifedata.com/resource/pubmed/chemical/Ethanolamines,
http://linkedlifedata.com/resource/pubmed/chemical/Methane,
http://linkedlifedata.com/resource/pubmed/chemical/Nitroparaffins,
http://linkedlifedata.com/resource/pubmed/chemical/Radiopharmaceuticals,
http://linkedlifedata.com/resource/pubmed/chemical/nitromethane
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
1464-3405
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:day |
1
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pubmed:volume |
19
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
3439-41
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pubmed:meshHeading | |
pubmed:year |
2009
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pubmed:articleTitle |
Synthesis of (11)C-labeled 2-aminoethanol via a nitroaldol reaction using nitro[(11)C]methane.
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pubmed:affiliation |
Department of Molecular Probes, National Institute of Radiological Sciences, 4-9-1 Anagawa, Inage-ku, Chiba 263-855, Japan. katok@nirs.go.jp
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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