Linked Life Data

19481582

Source:http://linkedlifedata.com/resource/pubmed/id/19481582

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1-2
pubmed:dateCreated
2009-9-23
pubmed:abstractText
Thyroid development has been intensively studied in the mouse, where it closely recapitulates the human situation. Despite the lack of a compact thyroid gland, the zebrafish thyroid tissue originates from the pharyngeal endoderm and the main genes involved in its patterning and early development are conserved between zebrafish and mammals. In recent years, the zebrafish has become a powerful model not only for the developmental biology studies, but also for large-scale genetic analyses and drug screenings, mostly thanks to the ease with which its embryos can be manipulated and to its translucent body, which allows in vivo imaging. In this review we will provide an overview of the current knowledge of thyroid gland origin and differentiation in the zebrafish. Moreover, we will consider the action of thyroid hormones and some aspects related to endocrine disruptors.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
1872-8057
pubmed:author
pubmed:issnType
Electronic
pubmed:day
27
pubmed:volume
312
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
14-23
pubmed:meshHeading
pubmed:year
2009
pubmed:articleTitle
Thyroid gland development and function in the zebrafish model.
pubmed:affiliation
Dipartimento di Scienze Mediche, Università degli Studi di Milano & Lab of Experimental Endocrinology, IRCCS Istituto Auxologico Italiano, Via Zucchi 18, 20095 Cusano, Milan, Italy. patrizia.porazzi@unimi.it
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't