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rdf:type |
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lifeskim:mentions |
|
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pubmed:issue |
5031
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pubmed:dateCreated |
1991-11-25
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pubmed:databankReference |
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pubmed:abstractText |
The action of dopamine and other monoamine neurotransmitters at synapses is terminated predominantly by high-affinity reuptake into presynaptic terminals by specific sodium-dependent neurotransmitter transport proteins. A complementary DNA encoding a rat dopamine transporter has been isolated that exhibits high sequence similarity with the previously cloned norepinephrine and gamma-aminobutyric acid transporters. Transient expression of the complementary DNA in HeLa cells confirms the cocaine sensitivity of this transporter.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0036-8075
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
25
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pubmed:volume |
254
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
578-9
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pubmed:dateRevised |
2007-3-19
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pubmed:meshHeading |
pubmed-meshheading:1948035-Amino Acid Sequence,
pubmed-meshheading:1948035-Animals,
pubmed-meshheading:1948035-Base Sequence,
pubmed-meshheading:1948035-Carrier Proteins,
pubmed-meshheading:1948035-Cloning, Molecular,
pubmed-meshheading:1948035-Cocaine,
pubmed-meshheading:1948035-Dopamine,
pubmed-meshheading:1948035-Dopamine Plasma Membrane Transport Proteins,
pubmed-meshheading:1948035-Gene Expression,
pubmed-meshheading:1948035-HeLa Cells,
pubmed-meshheading:1948035-Humans,
pubmed-meshheading:1948035-Kinetics,
pubmed-meshheading:1948035-Membrane Glycoproteins,
pubmed-meshheading:1948035-Membrane Transport Proteins,
pubmed-meshheading:1948035-Molecular Sequence Data,
pubmed-meshheading:1948035-Nerve Tissue Proteins,
pubmed-meshheading:1948035-Oligodeoxyribonucleotides,
pubmed-meshheading:1948035-Polymerase Chain Reaction,
pubmed-meshheading:1948035-Rats,
pubmed-meshheading:1948035-Sequence Homology, Nucleic Acid,
pubmed-meshheading:1948035-Transfection
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pubmed:year |
1991
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pubmed:articleTitle |
Cloning and expression of a cocaine-sensitive rat dopamine transporter.
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pubmed:affiliation |
Yale University, New Haven, CT 06510.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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