|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
6
|
|
pubmed:dateCreated |
2009-6-16
|
|
pubmed:abstractText |
GDF5 and FRZB have been proposed as genetic loci conferring susceptibility to osteoarthritis (OA); however, the results of several studies investigating the association of OA with the rs143383 polymorphism of the GDF5 gene or the rs7775 and rs288326 polymorphisms of the FRZB gene have been conflicting or inconclusive. To examine these associations, we performed a large-scale meta-analysis of individual-level data.
|
|
pubmed:grant |
http://linkedlifedata.com/resource/pubmed/grant/2 R01-AG-005394-22A1,
http://linkedlifedata.com/resource/pubmed/grant/2 R01-AG-027574-22A1,
http://linkedlifedata.com/resource/pubmed/grant/AG-05394,
http://linkedlifedata.com/resource/pubmed/grant/AG-05407,
http://linkedlifedata.com/resource/pubmed/grant/AR-35582,
http://linkedlifedata.com/resource/pubmed/grant/AR-35583,
http://linkedlifedata.com/resource/pubmed/grant/AR-35584,
http://linkedlifedata.com/resource/pubmed/grant/K24 AR048841-08,
http://linkedlifedata.com/resource/pubmed/grant/K24-AR-04884,
http://linkedlifedata.com/resource/pubmed/grant/R01-AG-005407,
http://linkedlifedata.com/resource/pubmed/grant/R01-AG-027576-22
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
AIM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Jun
|
|
pubmed:issn |
0004-3591
|
|
pubmed:author |
pubmed-author:CarrAndrewA,
pubmed-author:ChapmanKayK,
pubmed-author:DohertyMichaelM,
pubmed-author:DohertySallyS,
pubmed-author:Gómez-ReinoJuan JJJ,
pubmed-author:GonzalezAntonioA,
pubmed-author:HalldorssonBjarni VBV,
pubmed-author:HartDeborah JDJ,
pubmed-author:HaukssonValdimar BVB,
pubmed-author:HofmanAlbertA,
pubmed-author:IkegawaShiroS,
pubmed-author:IngvarssonThorvaldurT,
pubmed-author:IoannidisJohn P AJP,
pubmed-author:JiangQingQ,
pubmed-author:JonsdottirIngileifI,
pubmed-author:JonssonHelgiH,
pubmed-author:KarassaFotini BFB,
pubmed-author:KerkhofHanneke J MHJ,
pubmed-author:KloppenburgMargreetM,
pubmed-author:LaneNancy ENE,
pubmed-author:LoriesRik JRJ,
pubmed-author:LoughlinJohnJ,
pubmed-author:MeulenbeltIngridI,
pubmed-author:NäkkiAnnuA,
pubmed-author:NevittMichael CMC,
pubmed-author:OsL OLO,
pubmed-author:Rodriguez-LopezJulioJ,
pubmed-author:ShiDongquanD,
pubmed-author:SlagboomP ElinePE,
pubmed-author:SpectorTim DTD,
pubmed-author:StefanssonKariK,
pubmed-author:TsezouAspasiaA,
pubmed-author:UWW,
pubmed-author:UitterlindenAndre GAG,
pubmed-author:ValdesAna MAM,
pubmed-author:WallisGillian AGA,
pubmed-author:WatsonChristopher MCM,
pubmed-author:van MeursJoyce B JJB
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
60
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
1710-21
|
|
pubmed:dateRevised |
2010-12-3
|
|
pubmed:meshHeading |
pubmed-meshheading:19479880-Aged,
pubmed-meshheading:19479880-Aged, 80 and over,
pubmed-meshheading:19479880-Bayes Theorem,
pubmed-meshheading:19479880-Case-Control Studies,
pubmed-meshheading:19479880-Female,
pubmed-meshheading:19479880-Genetic Predisposition to Disease,
pubmed-meshheading:19479880-Glycoproteins,
pubmed-meshheading:19479880-Growth Differentiation Factor 5,
pubmed-meshheading:19479880-Hand Joints,
pubmed-meshheading:19479880-Haplotypes,
pubmed-meshheading:19479880-Humans,
pubmed-meshheading:19479880-Male,
pubmed-meshheading:19479880-Middle Aged,
pubmed-meshheading:19479880-Osteoarthritis,
pubmed-meshheading:19479880-Osteoarthritis, Hip,
pubmed-meshheading:19479880-Osteoarthritis, Knee,
pubmed-meshheading:19479880-Phenotype,
pubmed-meshheading:19479880-Polymorphism, Genetic
|
|
pubmed:year |
2009
|
|
pubmed:articleTitle |
Large-scale analysis of association between GDF5 and FRZB variants and osteoarthritis of the hip, knee, and hand.
|
|
pubmed:affiliation |
Department of Hygiene and Epidemiology, University of Ioannina School of Medicine, Ioannina, Greece.
|
|
pubmed:publicationType |
Journal Article
|
