rdf:type |
|
lifeskim:mentions |
umls-concept:C0016030,
umls-concept:C0017262,
umls-concept:C0018787,
umls-concept:C0021289,
umls-concept:C0022009,
umls-concept:C0034693,
umls-concept:C0034721,
umls-concept:C0185117,
umls-concept:C0225828,
umls-concept:C0443235,
umls-concept:C0457405,
umls-concept:C0597170,
umls-concept:C1521761,
umls-concept:C2911684
|
pubmed:issue |
4
|
pubmed:dateCreated |
2009-8-13
|
pubmed:abstractText |
The pathological proliferation of cardiac fibroblasts (CFs) in response to heart injury results in fibrosis, which correlates with arrhythmia generation and heart failure. Here we systematically examined the effect of fibroblast-derived paracrine factors on electrical propagation in cardiomyocytes.
|
pubmed:grant |
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Sep
|
pubmed:issn |
1755-3245
|
pubmed:author |
|
pubmed:issnType |
Electronic
|
pubmed:day |
1
|
pubmed:volume |
83
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
688-97
|
pubmed:dateRevised |
2010-9-2
|
pubmed:meshHeading |
pubmed-meshheading:19477968-Action Potentials,
pubmed-meshheading:19477968-Animals,
pubmed-meshheading:19477968-Animals, Newborn,
pubmed-meshheading:19477968-Apoptosis,
pubmed-meshheading:19477968-Cell Proliferation,
pubmed-meshheading:19477968-Cells, Cultured,
pubmed-meshheading:19477968-Connexin 43,
pubmed-meshheading:19477968-Culture Media, Conditioned,
pubmed-meshheading:19477968-Electrophysiological Phenomena,
pubmed-meshheading:19477968-Fibroblasts,
pubmed-meshheading:19477968-Gene Expression,
pubmed-meshheading:19477968-Ion Channels,
pubmed-meshheading:19477968-Membrane Potentials,
pubmed-meshheading:19477968-Myocardium,
pubmed-meshheading:19477968-Myocytes, Cardiac,
pubmed-meshheading:19477968-Myosin Heavy Chains,
pubmed-meshheading:19477968-Paracrine Communication,
pubmed-meshheading:19477968-Phosphorylation,
pubmed-meshheading:19477968-Rats
|
pubmed:year |
2009
|
pubmed:articleTitle |
Cardiac fibroblast paracrine factors alter impulse conduction and ion channel expression of neonatal rat cardiomyocytes.
|
pubmed:affiliation |
Biomedical Engineering Department, Duke University, Hudson Hall 136, Durham, NC 27708, USA.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
|