Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1991-12-9
pubmed:abstractText
The interpretation of results obtained by immunoassays is affected by many different factors and especially by assay sensitivity and specificity. The introduction of sandwich-type immunometric assays using highly sensitive non-radioactive labels and monoclonal antibodies has greatly improved sensitivity while reducing assay time and simplifying performance. Thus determination of subnormal levels of several hormones has become possible. This approach has also enabled more exact tuning of specificity but at the same time it has introduced the risk of too high selectivity. Hapten assays have also become simpler to perform, but in this case no substantial improvement in assay sensitivity has been achieved.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0085-591X
pubmed:author
pubmed:issnType
Print
pubmed:volume
205
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
86-94
pubmed:dateRevised
2005-11-16
pubmed:meshHeading
pubmed:year
1991
pubmed:articleTitle
Method dependence of interpretation of immunoassay results.
pubmed:affiliation
Dept Obst Gyn, Helsinki University Central Hospital, FI.
pubmed:publicationType
Journal Article, Review