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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
2009-7-15
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pubmed:abstractText |
C-C chemokine receptor 5 (CCR5) is involved in the regulation of the inflammatory response. Abdominal aortic aneurysms (AAA) may arise as the result of a chronic inflammatory process which is influenced by genetic predisposition. The CCR5 gene is associated with a 32 base pair deletion (the Delta32 polymorphism). The aim of this study was to investigate the role of the CCR5 Delta32 polymorphism in the development of AAA.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
1744-313X
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
36
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
199-205
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pubmed:meshHeading |
pubmed-meshheading:19476483-Aged,
pubmed-meshheading:19476483-Aged, 80 and over,
pubmed-meshheading:19476483-Alleles,
pubmed-meshheading:19476483-Aortic Aneurysm, Abdominal,
pubmed-meshheading:19476483-Case-Control Studies,
pubmed-meshheading:19476483-Comorbidity,
pubmed-meshheading:19476483-Female,
pubmed-meshheading:19476483-Gene Frequency,
pubmed-meshheading:19476483-Genetic Predisposition to Disease,
pubmed-meshheading:19476483-Heterozygote,
pubmed-meshheading:19476483-Homozygote,
pubmed-meshheading:19476483-Humans,
pubmed-meshheading:19476483-Inflammation,
pubmed-meshheading:19476483-Leukocytes, Mononuclear,
pubmed-meshheading:19476483-Male,
pubmed-meshheading:19476483-Middle Aged,
pubmed-meshheading:19476483-Polymorphism, Genetic,
pubmed-meshheading:19476483-Receptors, CCR5,
pubmed-meshheading:19476483-Smoking
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pubmed:year |
2009
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pubmed:articleTitle |
The role of the CCR5 Delta32 polymorphism in abdominal aortic aneurysms.
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pubmed:affiliation |
Leicester Royal Infirmary, Leicester, UK. bex125@hotmail.com
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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