Linked Life Data

19476339

Source:http://linkedlifedata.com/resource/pubmed/id/19476339

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
2009-6-23
pubmed:abstractText
A simple and novel electrostatic coupling method is reported, which provides a hyaluronic acid-quantum dot conjugate (HA-QD) that is colloidally stable and size-tunable from 50 to 120 nm. The HA-QDs show cancer targeting efficiency, which suggests diagnostic and imaging applications. The conjugates are also demonstrated for the fluorescence staining capability for lymphatic vessels in vitro and in vivo. Using the HA-QDs in a small animal model, lymphatic vessels are visualized real-time in vivo for days. Comprehensive cytotoxicity evaluations are made for the conjugates and the unconjugated counterpart. The HA-QDs showcase the potentials toward cancer imaging and real-time visualization of changes in lymphatic vessels such as lymphangiogenesis.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
1936-086X
pubmed:author
pubmed:issnType
Electronic
pubmed:day
23
pubmed:volume
3
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1389-98
pubmed:meshHeading
pubmed:year
2009
pubmed:articleTitle
Hyaluronic acid-quantum dot conjugates for in vivo lymphatic vessel imaging.
pubmed:affiliation
Department of Bioengineering, Hanyang University, Seoul 133-791, Korea.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't