|
rdf:type |
|
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lifeskim:mentions |
umls-concept:C0007595,
umls-concept:C0032105,
umls-concept:C0032120,
umls-concept:C0032790,
umls-concept:C0205322,
umls-concept:C0225336,
umls-concept:C0332281,
umls-concept:C0392747,
umls-concept:C0600210,
umls-concept:C0810152,
umls-concept:C1269955,
umls-concept:C1533691,
umls-concept:C2699153
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|
pubmed:issue |
6
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|
pubmed:dateCreated |
2009-6-2
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|
pubmed:abstractText |
Plasma vascular endothelial growth factor (VEGF) levels are elevated for weeks after minimally invasive colorectal resection (MICR). Decreased plasma angiopoietin-(Ang) 1 and increased Ang-2 levels have been noted on postoperative days (POD) 1 and 3. These proangiogenic changes may stimulate tumor growth postoperatively (postop). This study's purpose was to track plasma VEGF, Ang-1, and Ang-2 levels for 4 to 8 weeks after MICR for cancer and to assess the impact of preoperative (preop) and postop plasma on in vitro endothelial cell (EC) behavior.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
|
|
pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
1528-1140
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pubmed:author |
|
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pubmed:issnType |
Electronic
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pubmed:volume |
249
|
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pubmed:owner |
NLM
|
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pubmed:authorsComplete |
Y
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pubmed:pagination |
973-7
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pubmed:dateRevised |
2010-1-8
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pubmed:meshHeading |
pubmed-meshheading:19474682-Adenocarcinoma,
pubmed-meshheading:19474682-Aged,
pubmed-meshheading:19474682-Aged, 80 and over,
pubmed-meshheading:19474682-Angiopoietin-1,
pubmed-meshheading:19474682-Angiopoietin-2,
pubmed-meshheading:19474682-Cell Movement,
pubmed-meshheading:19474682-Cell Proliferation,
pubmed-meshheading:19474682-Cohort Studies,
pubmed-meshheading:19474682-Colectomy,
pubmed-meshheading:19474682-Colorectal Neoplasms,
pubmed-meshheading:19474682-Endothelial Cells,
pubmed-meshheading:19474682-Female,
pubmed-meshheading:19474682-Humans,
pubmed-meshheading:19474682-Male,
pubmed-meshheading:19474682-Middle Aged,
pubmed-meshheading:19474682-Retrospective Studies,
pubmed-meshheading:19474682-Surgical Procedures, Minimally Invasive,
pubmed-meshheading:19474682-Vascular Endothelial Growth Factor A
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pubmed:year |
2009
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pubmed:articleTitle |
Colorectal resection is associated with persistent proangiogenic plasma protein changes: postoperative plasma stimulates in vitro endothelial cell growth, migration, and invasion.
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pubmed:affiliation |
Columbia University College of Physicians and Surgeons, New York, New York, USA.
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pubmed:publicationType |
Journal Article,
Multicenter Study
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