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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
11
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pubmed:dateCreated |
2009-6-2
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pubmed:abstractText |
Mass spectrometry-based serum peptidome profiling is a promising tool to identify novel disease-associated biomarkers, but is limited by preanalytic factors and the intricacies of complex data processing. Therefore, we investigated whether standardized sample protocols and new bioinformatic tools combined with external data validation improve the validity of peptidome profiling for the discovery of pancreatic cancer-associated serum markers.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
1078-0432
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pubmed:author |
pubmed-author:BüchlerMarkusM,
pubmed-author:BaumannSvenS,
pubmed-author:CeglarekUtaU,
pubmed-author:ConradTimT,
pubmed-author:FelixKlausK,
pubmed-author:FiedlerGeorg MartinGM,
pubmed-author:HaussJohannJ,
pubmed-author:KaseJuliaJ,
pubmed-author:LeichtleAlexander BenediktAB,
pubmed-author:SchütteChristofC,
pubmed-author:ThieryJoachimJ,
pubmed-author:WeimannArvedA,
pubmed-author:WitzigmannHelmutH
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pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
15
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
3812-9
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pubmed:meshHeading |
pubmed-meshheading:19470732-Blood Proteins,
pubmed-meshheading:19470732-CA-19-9 Antigen,
pubmed-meshheading:19470732-Carcinoembryonic Antigen,
pubmed-meshheading:19470732-Diagnosis, Differential,
pubmed-meshheading:19470732-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:19470732-Humans,
pubmed-meshheading:19470732-Pancreatic Neoplasms,
pubmed-meshheading:19470732-Platelet Factor 4,
pubmed-meshheading:19470732-Proteomics,
pubmed-meshheading:19470732-Reproducibility of Results,
pubmed-meshheading:19470732-Sensitivity and Specificity,
pubmed-meshheading:19470732-Spectrometry, Mass, Matrix-Assisted Laser...,
pubmed-meshheading:19470732-Tumor Markers, Biological
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pubmed:year |
2009
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pubmed:articleTitle |
Serum peptidome profiling revealed platelet factor 4 as a potential discriminating Peptide associated with pancreatic cancer.
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pubmed:affiliation |
Institute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics, University Hospital Leipzig, Leipzig, Germany.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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