|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0000677,
umls-concept:C0015637,
umls-concept:C0021368,
umls-concept:C0162638,
umls-concept:C1123023,
umls-concept:C1280500,
umls-concept:C1314939,
umls-concept:C1326912,
umls-concept:C1516463,
umls-concept:C1704259,
umls-concept:C1705987
|
|
pubmed:issue |
5-6
|
|
pubmed:dateCreated |
2009-7-14
|
|
pubmed:abstractText |
Naturally-derived farnesol has been reported for its chemopreventive and chemotherapeutic efficacy in various cancers. However, the mechanism of action of farnesol is still to be elucidated. The present study demonstrates the chemopreventive potential of farnesol on 9,10-dimethylbenz(a)anthracene (DMBA)-initiated and 12-O-tetradecanoylphorbol-13-acetate (TPA)-promoted skin tumorigenesis in Swiss albino mice.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/9,10-Dimethyl-1,2-benzanthracene,
http://linkedlifedata.com/resource/pubmed/chemical/Anticarcinogenic Agents,
http://linkedlifedata.com/resource/pubmed/chemical/Cyclooxygenase 2,
http://linkedlifedata.com/resource/pubmed/chemical/Extracellular Signal-Regulated MAP...,
http://linkedlifedata.com/resource/pubmed/chemical/Farnesol,
http://linkedlifedata.com/resource/pubmed/chemical/Ornithine Decarboxylase,
http://linkedlifedata.com/resource/pubmed/chemical/Ptgs2 protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Tetradecanoylphorbol Acetate,
http://linkedlifedata.com/resource/pubmed/chemical/ras Proteins
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Jul
|
|
pubmed:issn |
1879-0631
|
|
pubmed:author |
|
|
pubmed:issnType |
Electronic
|
|
pubmed:day |
31
|
|
pubmed:volume |
85
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
196-205
|
|
pubmed:dateRevised |
2009-11-19
|
|
pubmed:meshHeading |
pubmed-meshheading:19470390-9,10-Dimethyl-1,2-benzanthracene,
pubmed-meshheading:19470390-Animals,
pubmed-meshheading:19470390-Anticarcinogenic Agents,
pubmed-meshheading:19470390-Apoptosis,
pubmed-meshheading:19470390-Chemoprevention,
pubmed-meshheading:19470390-Cyclooxygenase 2,
pubmed-meshheading:19470390-Disease Models, Animal,
pubmed-meshheading:19470390-Drug Screening Assays, Antitumor,
pubmed-meshheading:19470390-Extracellular Signal-Regulated MAP Kinases,
pubmed-meshheading:19470390-Farnesol,
pubmed-meshheading:19470390-Inflammation,
pubmed-meshheading:19470390-Mice,
pubmed-meshheading:19470390-Ornithine Decarboxylase,
pubmed-meshheading:19470390-Oxidative Stress,
pubmed-meshheading:19470390-Skin,
pubmed-meshheading:19470390-Skin Neoplasms,
pubmed-meshheading:19470390-Tetradecanoylphorbol Acetate,
pubmed-meshheading:19470390-ras Proteins
|
|
pubmed:year |
2009
|
|
pubmed:articleTitle |
Chemopreventive effect of farnesol on DMBA/TPA-induced skin tumorigenesis: involvement of inflammation, Ras-ERK pathway and apoptosis.
|
|
pubmed:affiliation |
Department of Medical Elementology and Toxicology, Faculty of Science, Jamia Hamdard, Hamdard Nagar, New Delhi-110062, India. sandeepcchaudhary@rediffmail.com
|
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
