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pubmed-article:19466885pubmed:abstractTextWe have attempted to micronize drug particles with a particle size of less than 100 nm and maintain the particle size of their suspension to improve the solubility and bioavailability of poorly water-soluble drugs. Furthermore, the method of freeze-drying nanoparticles was applied to maintain particulate nature of nanoparticles containing various saccharides and sugar alcohols for a long time.lld:pubmed
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pubmed-article:19466885pubmed:articleTitlePreparation of griseofulvin nanoparticle suspension by high-pressure homogenization and preservation of the suspension with saccharides and sugar alcohols.lld:pubmed
pubmed-article:19466885pubmed:affiliationFaculty of Pharmaceutical Sciences, Nagasaki International University, Sasebo, Nagasaki, Japan. kamiya@niu.ac.jplld:pubmed
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