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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
8
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pubmed:dateCreated |
2009-7-28
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pubmed:abstractText |
We have attempted to micronize drug particles with a particle size of less than 100 nm and maintain the particle size of their suspension to improve the solubility and bioavailability of poorly water-soluble drugs. Furthermore, the method of freeze-drying nanoparticles was applied to maintain particulate nature of nanoparticles containing various saccharides and sugar alcohols for a long time.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
1520-5762
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
35
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1022-8
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pubmed:meshHeading |
pubmed-meshheading:19466885-Antifungal Agents,
pubmed-meshheading:19466885-Biological Availability,
pubmed-meshheading:19466885-Drug Stability,
pubmed-meshheading:19466885-Erythritol,
pubmed-meshheading:19466885-Excipients,
pubmed-meshheading:19466885-Freeze Drying,
pubmed-meshheading:19466885-Griseofulvin,
pubmed-meshheading:19466885-Lactose,
pubmed-meshheading:19466885-Nanoparticles,
pubmed-meshheading:19466885-Particle Size,
pubmed-meshheading:19466885-Solubility,
pubmed-meshheading:19466885-Sucrose,
pubmed-meshheading:19466885-Suspensions,
pubmed-meshheading:19466885-Trehalose,
pubmed-meshheading:19466885-Xylitol
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pubmed:year |
2009
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pubmed:articleTitle |
Preparation of griseofulvin nanoparticle suspension by high-pressure homogenization and preservation of the suspension with saccharides and sugar alcohols.
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pubmed:affiliation |
Faculty of Pharmaceutical Sciences, Nagasaki International University, Sasebo, Nagasaki, Japan. kamiya@niu.ac.jp
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pubmed:publicationType |
Journal Article
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