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rdf:type |
|
|
lifeskim:mentions |
|
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pubmed:issue |
7
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pubmed:dateCreated |
2009-6-22
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pubmed:abstractText |
The term benign multiple sclerosis (BMS) is referred to patients who have a mild or absent disability several years after disease clinical onset. Axonal damage can be measured in vivo using proton MR spectroscopy ((1)H-MRS). In this study, we quantified the severity of "global" axonal damage in BMS and early relapsing-remitting (RR) MS patients, using whole brain N-acetylaspartate (WBNAA) (1)H-MRS, to better elucidate the structural correlates of a non-disabling disease evolution.
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pubmed:language |
eng
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pubmed:journal |
|
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pubmed:citationSubset |
IM
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|
pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
|
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pubmed:issn |
1352-4585
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pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:volume |
15
|
|
pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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|
pubmed:pagination |
789-94
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pubmed:meshHeading |
pubmed-meshheading:19465450-Adult,
pubmed-meshheading:19465450-Aspartic Acid,
pubmed-meshheading:19465450-Axons,
pubmed-meshheading:19465450-Biological Markers,
pubmed-meshheading:19465450-Brain,
pubmed-meshheading:19465450-Brain Chemistry,
pubmed-meshheading:19465450-Cell Survival,
pubmed-meshheading:19465450-Cross-Sectional Studies,
pubmed-meshheading:19465450-Disability Evaluation,
pubmed-meshheading:19465450-Disease Progression,
pubmed-meshheading:19465450-Female,
pubmed-meshheading:19465450-Humans,
pubmed-meshheading:19465450-Magnetic Resonance Imaging,
pubmed-meshheading:19465450-Magnetic Resonance Spectroscopy,
pubmed-meshheading:19465450-Male,
pubmed-meshheading:19465450-Middle Aged,
pubmed-meshheading:19465450-Multiple Sclerosis,
pubmed-meshheading:19465450-Multiple Sclerosis, Relapsing-Remitting,
pubmed-meshheading:19465450-Severity of Illness Index,
pubmed-meshheading:19465450-Young Adult
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|
pubmed:year |
2009
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|
pubmed:articleTitle |
In-vivo evidence for stable neuroaxonal damage in the brain of patients with benign multiple sclerosis.
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|
pubmed:affiliation |
Neuroimaging Research Unit, Scientific Institute and University Ospedale San Raffaele, Milan, Italy.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|
