Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
13
pubmed:dateCreated
2009-6-9
pubmed:abstractText
1,N(6)-Ethenoadenosine derivatives have been applied as fluorescence probes in various fields of biochemistry and molecular biology. We developed a 1,N(6)-ethenoadenosine-forming reaction at a target adenine in DNA duplex and applied it to a mutation diagnosis. Furan-derivatized oligodeoxyribonucleotides were synthesized and fluorescence properties were studied in the presence of complementary strand under oxidative conditions. Strong emissions at 430nm were observed in the presence of the complementary strand with an adenine in front of furan moiety.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
1464-3405
pubmed:author
pubmed:issnType
Electronic
pubmed:day
1
pubmed:volume
19
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
3657-60
pubmed:meshHeading
pubmed:year
2009
pubmed:articleTitle
Sequence selective formation of 1,N(6)-ethenoadenine in DNA by furan-conjugated probe.
pubmed:affiliation
Kyoto Institute of Technology, Graduate School of Science and Technology, Department of Biomolecular Engineering, Kyoto, Japan. akobori@kit.ac.jp
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't