The frequency, characteristics and impact of acute exacerbations in patients with alpha-1 antitrypsin deficiency (AATD) and COPD who are on intravenous alpha-1 antitrypsin augmentation therapy have not been described.
University of Miami Miller School of Medicine, Division of Pulmonary and Critical Care Medicine, P.O. Box 016960 (R-47), Miami, FL 33101, USA. mcampos1@med.miami.edu