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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
2009-5-22
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pubmed:abstractText |
Subclinical endotoxemia has been reported in HIV-1 infected persons and may drive systemic immune activation and pathogenesis. Proinflammatory responsiveness to endotoxin (LPS) is mediated by Toll-like receptor 4 (TLR4). We therefore examined the association between plasma LPS levels, HIV RNA, and TLR4 expression and cytokine responses in the blood of HIV infected and uninfected participants in a cohort of female sex-workers in Kenya.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1932-6203
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
4
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
e5644
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:19461969-Adult,
pubmed-meshheading:19461969-Cytokines,
pubmed-meshheading:19461969-Endotoxemia,
pubmed-meshheading:19461969-Female,
pubmed-meshheading:19461969-Gene Expression Regulation,
pubmed-meshheading:19461969-HIV Infections,
pubmed-meshheading:19461969-HIV-1,
pubmed-meshheading:19461969-Humans,
pubmed-meshheading:19461969-Immune Tolerance,
pubmed-meshheading:19461969-Kenya,
pubmed-meshheading:19461969-Lipopolysaccharides,
pubmed-meshheading:19461969-Lymphocytes,
pubmed-meshheading:19461969-Middle Aged,
pubmed-meshheading:19461969-Prostitution,
pubmed-meshheading:19461969-RNA, Messenger,
pubmed-meshheading:19461969-RNA, Viral,
pubmed-meshheading:19461969-Signal Transduction,
pubmed-meshheading:19461969-Toll-Like Receptor 4,
pubmed-meshheading:19461969-Toll-Like Receptors
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pubmed:year |
2009
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pubmed:articleTitle |
HIV-1 RNA dysregulates the natural TLR response to subclinical endotoxemia in Kenyan female sex-workers.
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pubmed:affiliation |
Department of Medical Microbiology and Infectious Diseases, University of Manitoba, Winnipeg, Manitoba, Canada. rlester.id@gmail.com
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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