Linked Life Data

19461655

Source:http://linkedlifedata.com/resource/pubmed/id/19461655

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2010-1-11
pubmed:abstractText
The microRNA (miRNA) miR-10 family has attracted attention because of its conservation and the position of the miR-10 genes within the Hox clusters of developmental regulators. In several species, miR-10 is coexpressed with a set of Hox genes and has been found to regulate the translation of Hox transcripts. In addition, members of the miR-10 family are de-regulated in several cancer forms. Aside from acting in translational repression, miR-10 was recently found to bind a group of transcripts containing a terminal oligo-pyrimidine (TOP) motif and to induce their translation, thereby adding a new function to the miRNA repertoire.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
1476-5403
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
17
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
209-14
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
miR-10 in development and cancer.
pubmed:affiliation
Biotech Research and Innovation Centre and Center for Epigenetics, University of Copenhagen, Ole Maaløes Vej 5, DK-2200 Copenhagen, Denmark. anders.lund@bric.dk
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't