Linked Life Data

1946076

Source:http://linkedlifedata.com/resource/pubmed/id/1946076

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1991-11-25
pubmed:abstractText
Sudden infant death syndrome (SIDS) infants have significantly thicker and more cellular bronchiolar walls than control infants of similar age. A morphometric study of 25 SIDS and 18 control infants was undertaken to measure the bronchiolar wall thickness using a Cue-2 image analysis system. A mathematical formula (relative index) was used to compare the thickness of bronchioles of varying diameter. Data analysis using a nested design two-way analysis of variance and covariance of the measured bronchioles showed a significant difference between the SIDS and control infants with a P value less than .001. Manual counting of the cells in the bronchiolar walls and data analysis using an unpaired two-tailed t test showed that the SIDS infants had a significantly greater number of cells than control infants (P less than .01). Our preliminary results indicate that the cells in the bronchiolar wall are either peripheral nerve-derived (Schwann cells) or Langerhans cells. We postulate that these cells are increased in number in response to chronic hypoxia in SIDS infants.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
0277-0938
pubmed:author
pubmed:issnType
Print
pubmed:volume
11
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
551-68
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:articleTitle
Bronchiolar wall changes in sudden infant death syndrome: morphometric study of a new observation.
pubmed:affiliation
Department of Pathology, University of Texas Medical Branch, Galveston 77550.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't