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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
Pt 9
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pubmed:dateCreated |
2009-8-13
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pubmed:databankReference |
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/AB475143,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/AB475144,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/AB475145,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/AB475146,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/AB475147,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/AB475148,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/AB475149,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/AB475150,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/AB475151,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/AB475152,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/AB475153,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/AB500121,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/AB500122,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/AB500123
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pubmed:abstractText |
Human adenovirus type 8 (HAdV-8) and 37 (HAdV-37) cause epidemic keratoconjunctivitis (EKC) associated with community-acquired and nosocomial infections. The nucleotide sequences of the entire hexon and fiber genes of eight HAdV-8 and 26 HAdV-37 strains were analysed and the transition mutations in each gene were compared among strains. Compared with prototype strains, the hexon gene of HAdV-8 and -37 strains showed between two and seven and one and twelve variations at nine and 21 different positions, respectively. All of these, except one position in HAdV-37, were located in the conserved region 4 (C4). There were only three polymorphisms in the fiber gene of both HAdV-8 and HAdV-37, fewer than those in C4. The nucleotide sequence of HAdV-8 and -37 C4 might be readily modified during EKC epidemics.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0022-1317
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
90
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2260-5
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pubmed:meshHeading |
pubmed-meshheading:19458172-Adenovirus Infections, Human,
pubmed-meshheading:19458172-Adenoviruses, Human,
pubmed-meshheading:19458172-Base Sequence,
pubmed-meshheading:19458172-Capsid Proteins,
pubmed-meshheading:19458172-Disease Outbreaks,
pubmed-meshheading:19458172-Genetic Variation,
pubmed-meshheading:19458172-Humans,
pubmed-meshheading:19458172-Japan,
pubmed-meshheading:19458172-Keratoconjunctivitis,
pubmed-meshheading:19458172-Molecular Sequence Data,
pubmed-meshheading:19458172-Mutation,
pubmed-meshheading:19458172-Phylogeny
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pubmed:year |
2009
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pubmed:articleTitle |
Nucleotide sequence variation in the hexon gene of human adenovirus type 8 and 37 strains from epidemic keratoconjunctivitis patients in Japan.
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pubmed:affiliation |
Department of Microbiology, Fukushima Medical University School of Medicine, Fukushima, Japan. h-kane@chive.ocn.ne.jp
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pubmed:publicationType |
Journal Article
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