Source:http://linkedlifedata.com/resource/pubmed/id/19457896
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
2
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| pubmed:dateCreated |
2009-7-24
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| pubmed:abstractText |
The purpose of the present study was to retrospectively analyze the clinicopathological characteristics and clarify whether or not the preoperative carcinoembryonic antigen (CEA) level could be used as a decision-making factor as an adjunct to the TNM staging system in patients with clinical stage I non-small cell lung cancer (NSCLC). Between 1993 and 2006, 815 patients who had clinical stage I NSCLC were analyzed retrospectively. The CEA level was defined as being either normal (CEA<or=5 ng/ml), high (5<CEA<or=30 ng/ml) and very high (CEA>30 ng/ml) sub-groups. The rate of patients with an elevated CEA level was 33.6%. The five-year disease-free survival rates for patients with normal, high and very high CEA levels were 76.7, 60.0 and 31.3%, respectively. The survival curve for patients with a normal CEA level almost overlapped that for p-stage I, that for a high CEA level nearly overlapped that for p-stage II, and that for a very high CEA level nearly overlapped that for p-stage III. The present study demonstrated that the preoperative CEA level was a very good predictor of the pathological stage. These findings suggest that the preoperative CEA level may be useful as an adjunct to the TNM staging system.
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| pubmed:language |
eng
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| pubmed:journal | |
| pubmed:citationSubset |
IM
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| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Aug
|
| pubmed:issn |
1569-9285
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| pubmed:author | |
| pubmed:issnType |
Electronic
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| pubmed:volume |
9
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| pubmed:owner |
NLM
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| pubmed:authorsComplete |
Y
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| pubmed:pagination |
199-202
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| pubmed:dateRevised |
2010-11-18
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| pubmed:meshHeading |
pubmed-meshheading:19457896-Aged,
pubmed-meshheading:19457896-Carcinoembryonic Antigen,
pubmed-meshheading:19457896-Carcinoma, Non-Small-Cell Lung,
pubmed-meshheading:19457896-Disease-Free Survival,
pubmed-meshheading:19457896-Female,
pubmed-meshheading:19457896-Humans,
pubmed-meshheading:19457896-Kaplan-Meier Estimate,
pubmed-meshheading:19457896-Lung Neoplasms,
pubmed-meshheading:19457896-Male,
pubmed-meshheading:19457896-Neoplasm Staging,
pubmed-meshheading:19457896-Odds Ratio,
pubmed-meshheading:19457896-Predictive Value of Tests,
pubmed-meshheading:19457896-Preoperative Care,
pubmed-meshheading:19457896-Proportional Hazards Models,
pubmed-meshheading:19457896-Retrospective Studies,
pubmed-meshheading:19457896-Risk Assessment,
pubmed-meshheading:19457896-Risk Factors,
pubmed-meshheading:19457896-Time Factors,
pubmed-meshheading:19457896-Treatment Outcome,
pubmed-meshheading:19457896-Up-Regulation
|
| pubmed:year |
2009
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| pubmed:articleTitle |
Clinical significance of preoperative carcinoembryonic antigen level for clinical stage I non-small cell lung cancer: can preoperative carcinoembryonic antigen level predict pathological stage?
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| pubmed:affiliation |
Thoracic Surgery Division, Kyorin University Hospital, Mitaka-shi, Tokyo 181-0004, Japan. rkawachi@kpe.biglobe.ne.jp
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| pubmed:publicationType |
Journal Article
|