Linked Life Data

19456391

Source:http://linkedlifedata.com/resource/pubmed/id/19456391

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2009-5-21
pubmed:abstractText
Here we show that genistein, through an estrogen receptor-mediated action, modulates gene expression in the mouse testis throughout development. Genistein passed from the lactating mother to the suckling offspring at levels sufficient to activate gene expression in the testis of the pups. Testis are already responsive to genistein as well as to estradiol at day 14.5 of fetal development. Activation of luciferase correlates with an activation of cell proliferation. In conclusion, our results show that genistein affects reproductive organs of male mice at all developmental ages.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
1749-6632
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
1163
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
475-7
pubmed:meshHeading
pubmed:year
2009
pubmed:articleTitle
Estrogen receptor-mediated transcriptional activity of genistein in the mouse testis.
pubmed:affiliation
Laboratory of Biotechnology, Civic Hospital of Brescia, Brescia, Italy.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't