Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2009-5-21
pubmed:abstractText
Recent studies in trout have shown that tachykinins might be selectively implicated in important neuroregulatory functions related to the central control of ventilation. In teleost fish, cardiorespiratory coupling probably contributes to heart rate variability (HRV), and the hypoventilatory effects observed after central injection of tachykinins suggest that these peptides also may produce changes in HRV. Consequently, the present study was undertaken to compare the central actions of picomolar doses (25-250 pmol) of trout neuropeptide gamma (NPgamma), substance P (SP), and neurokinin A (NKA) on HRV in unanesthetized rainbow trout. Compared to vehicle-injected trout, Poincaré plot analysis of HRV demonstrated that intracerebroventricular injection of NPgamma dose dependently increased HRV. SP evoked a significant elevation of HRV but only at the highest dose (250 pmol). In contrast, NKA was without any effect on HRV. In conclusion, these results suggest that NPgamma may be selectively implicated in the central control of HRV in trout.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
1749-6632
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
1163
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
379-82
pubmed:meshHeading
pubmed:year
2009
pubmed:articleTitle
Central effects of trout tachykinins on heart rate variability in trout.
pubmed:affiliation
Université Européenne de Bretagne, Université de Brest, Institut National de la Santé et de la Recherche Médicale (U650), Centre Hospitalier Universitaire de Brest, Brest, France.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't