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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2009-5-20
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pubmed:abstractText |
Cytochrome P450 2A6 (CYP2A6) is an important metabolic enzyme capable of activating several procarcinogens, including dietary and tobacco-specific nitrosamines, which have been linked to pancreatic cancer. Positive associations between high CYP2A6 activity and lung and colorectal cancers have been reported. This is the first investigation of CYP2A6 activity and pancreatic cancer.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1590-8577
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
10
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
263-70
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pubmed:dateRevised |
2009-9-18
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pubmed:meshHeading |
pubmed-meshheading:19454817-Adult,
pubmed-meshheading:19454817-Aged,
pubmed-meshheading:19454817-Aged, 80 and over,
pubmed-meshheading:19454817-Aryl Hydrocarbon Hydroxylases,
pubmed-meshheading:19454817-Caffeine,
pubmed-meshheading:19454817-Carcinogens,
pubmed-meshheading:19454817-Case-Control Studies,
pubmed-meshheading:19454817-Enzyme Activation,
pubmed-meshheading:19454817-Female,
pubmed-meshheading:19454817-Genetic Predisposition to Disease,
pubmed-meshheading:19454817-Humans,
pubmed-meshheading:19454817-Male,
pubmed-meshheading:19454817-Meat,
pubmed-meshheading:19454817-Middle Aged,
pubmed-meshheading:19454817-Midwestern United States,
pubmed-meshheading:19454817-Pancreatic Neoplasms,
pubmed-meshheading:19454817-Phenotype,
pubmed-meshheading:19454817-Risk Factors,
pubmed-meshheading:19454817-Smoking,
pubmed-meshheading:19454817-Young Adult
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pubmed:year |
2009
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pubmed:articleTitle |
Phenotypic CYP2A6 variation and the risk of pancreatic cancer.
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pubmed:affiliation |
Department of Environmental and Occupational Health, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA. sakadlubar@uams.edu
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pubmed:publicationType |
Journal Article,
Research Support, N.I.H., Extramural
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