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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
2009-8-26
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pubmed:abstractText |
As a pro-inflammatory cytokine, interleukin-2 mediates the activation, growth and differentiation of T and B lymphocytes and natural killer cells. Promoter polymorphisms of the interleukin-2 gene have been associated with altered interleukin-2 production or identified as prognostic markers for various infectious diseases. Therefore, the aim of this study was to evaluate two polymorphisms at positions -330 T/G and 166 G/T in patients with generalized chronic periodontitis (n = 58) or generalized aggressive periodontitis (n = 73) in comparison with periodontitis-free controls (n = 69).
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
D
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
1600-0765
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
44
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
628-35
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pubmed:meshHeading |
pubmed-meshheading:19453859-Actinobacillus actinomycetemcomitans,
pubmed-meshheading:19453859-Adult,
pubmed-meshheading:19453859-Aggressive Periodontitis,
pubmed-meshheading:19453859-Alleles,
pubmed-meshheading:19453859-Bacteroides,
pubmed-meshheading:19453859-Chronic Periodontitis,
pubmed-meshheading:19453859-Female,
pubmed-meshheading:19453859-Gene Frequency,
pubmed-meshheading:19453859-Genotype,
pubmed-meshheading:19453859-Guanine,
pubmed-meshheading:19453859-Haplotypes,
pubmed-meshheading:19453859-Humans,
pubmed-meshheading:19453859-Interleukin-2,
pubmed-meshheading:19453859-Male,
pubmed-meshheading:19453859-Middle Aged,
pubmed-meshheading:19453859-Periodontal Attachment Loss,
pubmed-meshheading:19453859-Periodontal Pocket,
pubmed-meshheading:19453859-Polymorphism, Genetic,
pubmed-meshheading:19453859-Porphyromonas gingivalis,
pubmed-meshheading:19453859-Prevotella intermedia,
pubmed-meshheading:19453859-Promoter Regions, Genetic,
pubmed-meshheading:19453859-Thymine,
pubmed-meshheading:19453859-Treponema denticola
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pubmed:year |
2009
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pubmed:articleTitle |
Interleukin-2 -330 and 166 gene polymorphisms in relation to aggressive or chronic periodontitis and the presence of periodontopathic bacteria.
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pubmed:affiliation |
University School of Dental Medicine, Department of Operative Dentistry and Periodontology, Martin-Luther University Halle-Wittenberg, Halle (Saale), Germany. stefan.reichert@medizin.uni-halle.de
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pubmed:publicationType |
Journal Article,
Comparative Study
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