Linked Life Data

19453159

Source:http://linkedlifedata.com/resource/pubmed/id/19453159

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
8
pubmed:dateCreated
2009-8-7
pubmed:abstractText
An NMR-metabonomic study of malformed fetuses was carried out through human amniotic fluid (HAF) analysis. Over 70 compounds were detected in control HAF by NMR. Possible confounding variables (fetus gender and gestational and maternal ages) were shown not to induce detectable compositional trends in the control group considered. Malformed fetuses showed variations in glucose, some amino acids and organic acids and proteins. In tandem with enzymatic assays, these NMR results suggest that changes in gycolysis and gluconeogenesis as well as kidney underdevelopment occur in the malformed fetuses studied here.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
1535-3893
pubmed:author
pubmed:issnType
Print
pubmed:volume
8
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
4144-50
pubmed:meshHeading
pubmed:year
2009
pubmed:articleTitle
(1)H NMR based metabonomics of human amniotic fluid for the metabolic characterization of fetus malformations.
pubmed:affiliation
CICECO, Department of Chemistry, University of Aveiro, Portugal.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't