Linked Life Data

19452986

Source:http://linkedlifedata.com/resource/pubmed/id/19452986

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
2009-5-20
pubmed:abstractText
The bioactivities, including the anti-inflammatory activity and influences on the learning function and the immunosuppression activity, of C60-dexamethasone have been studied in mice and compared with those of dexamethasone. C60-dexamethasone and dexamethasone were administered orally at dosage of 30 micromol/kg x d. The experiments showed that C60-dexamethasone retained the anti-inflammatory activity. On the other side the influences of C60-dexamethasone on the learning function and the immunosuppression activity were much lower than that of dexamethasone. The scavenging test for lipophilic DPPH free radical indicated that C60-dexamethasone was an efficient free radical remover or antioxidant, which was responsible for the reduction of side effects of C60-dexamethasone.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
1533-4880
pubmed:author
pubmed:issnType
Print
pubmed:volume
9
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
3171-6
pubmed:meshHeading
pubmed:year
2009
pubmed:articleTitle
Research on the bioactivities of C60-dexamethasone.
pubmed:affiliation
Laboratory of Nano-Biology and Medicine, Shanghai Institute of Applied Physics, Chinese Academy of Science, Shanghai 201800, China.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't