Linked Life Data

19449436

Source:http://linkedlifedata.com/resource/pubmed/id/19449436

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2009-7-29
pubmed:abstractText
Short T(2) species such as the Achilles tendon and cortical bone cannot be imaged with conventional MR sequences. They have a much broader absorption lineshape than long T(2) species, therefore they are more sensitive to an appropriately placed off-resonance irradiation. In this work, a technique termed ultrashort TE (UTE) with off-resonance saturation contrast (UTE-OSC) is proposed to image short T(2) species. A high power saturation pulse was placed +1 to +2 kHz off the water peak to preferentially saturate signals from short T(2) species, leaving long T(2) water and fat signals largely unaffected. The subtraction of UTE images with and without an off-resonance saturation pulse effectively suppresses long T(2) water and fat signals, creating high contrast for short T(2) species. The UTE-OSC technique was validated on a phantom, and applied to bone samples and healthy volunteers on a clinical 3T scanner. High-contrast images of the Achilles tendon and cortical bone were generated with a high contrast-to-noise ratio (CNR) of the order of 12 to 20 between short T(2) and long T(2) species within a total scan time of 4 to 10 min.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
1522-2594
pubmed:author
pubmed:copyrightInfo
(c) 2009 Wiley-Liss, Inc.
pubmed:issnType
Electronic
pubmed:volume
62
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
527-31
pubmed:meshHeading
pubmed:year
2009
pubmed:articleTitle
Ultrashort TE imaging with off-resonance saturation contrast (UTE-OSC).
pubmed:affiliation
Department of Radiology, University of California, San Diego, San Diego, CA 92103-8756, USA. jiangdu@ucsd.edu
pubmed:publicationType
Journal Article