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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
2009-6-2
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pubmed:abstractText |
Lithium remains a first-line treatment for bipolar disorder, but the mechanisms by which it prevents the recurrence of mood episodes are not known. The authors utilized data from a genomewide association study to examine associations between single nucleotide polymorphisms (SNPs) and the outcome of lithium treatment in two cohorts of patients with bipolar I disorder or bipolar II disorder.
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pubmed:grant |
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
1535-7228
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pubmed:author |
pubmed-author:BassNickN,
pubmed-author:FerreiraManuel A RMA,
pubmed-author:GurlingHughH,
pubmed-author:LawrenceJacobJ,
pubmed-author:McQuillinAndrewA,
pubmed-author:NimgaonkarVishwajitV,
pubmed-author:PerlisRoy HRH,
pubmed-author:PurcellShaunS,
pubmed-author:SachsGary SGS,
pubmed-author:ScolnickEdward MEM,
pubmed-author:SklarPamelaP,
pubmed-author:SmollerJordan WJW
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pubmed:issnType |
Electronic
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pubmed:volume |
166
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
718-25
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pubmed:meshHeading |
pubmed-meshheading:19448189-Adult,
pubmed-meshheading:19448189-Alleles,
pubmed-meshheading:19448189-Antipsychotic Agents,
pubmed-meshheading:19448189-Bipolar Disorder,
pubmed-meshheading:19448189-Chromosomes, Human, Pair 4,
pubmed-meshheading:19448189-Diagnostic and Statistical Manual of Mental Disorders,
pubmed-meshheading:19448189-Female,
pubmed-meshheading:19448189-Genome,
pubmed-meshheading:19448189-Genotype,
pubmed-meshheading:19448189-Humans,
pubmed-meshheading:19448189-Lithium Carbonate,
pubmed-meshheading:19448189-Male,
pubmed-meshheading:19448189-Polymorphism, Single Nucleotide,
pubmed-meshheading:19448189-Receptors, AMPA,
pubmed-meshheading:19448189-Recurrence
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pubmed:year |
2009
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pubmed:articleTitle |
A genomewide association study of response to lithium for prevention of recurrence in bipolar disorder.
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pubmed:affiliation |
Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA. rperlis@partners.org
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Research Support, Non-U.S. Gov't,
Multicenter Study,
Research Support, N.I.H., Extramural
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