Linked Life Data

19448013

Source:http://linkedlifedata.com/resource/pubmed/id/19448013

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
2009-5-18
pubmed:abstractText
The aim of the experiment was to determine the effects of 2 different fat supplementations on immune functions of dairy cows under high ambient temperatures. The experiment involved 24 Italian Friesian cows, divided into 3 groups of 8 animals, that were subjected to fat supplementations based on whole flaxseed (FS) or microencapsulated fish oil (FO). At d 0, 45, and 90 of the experiment, lymphocyte response to phytohemagglutinin (PHA) was determined in vivo on each animal by measurement of skin-fold thickness at the site of PHA injection. A humoral response to chicken egg albumin (OVA) was established following a subcutaneous injection with OVA. To assess cows' immune responses, plasma was prepared from experimental blood samples taken at d 0, 15, 30, 45, 60, 75, and 90 of the experiment. Plasma samples were measured for the presence of anti-OVA IgG, IL-1beta, IL-6, and IL-10. Results revealed greater skin-fold thickness in cows fed FS compared with the FO and the control groups, corresponding to higher mean lymphocyte proliferation following in vivo PHA injection. Cows fed FS displayed higher titers of anti-OVA IgG than the control and FO-fed cows. No effects of the diet on IL-1beta or IL-6 were found, whereas IL-10 secretion was lower in FS-fed cows than in control cows. The present study demonstrates that feed supplementation of n-3 polyunsaturated fatty acids can enhance immune responses of dairy cows exposed to high ambient temperatures.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
1525-3198
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
92
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
2796-803
pubmed:meshHeading
pubmed:year
2009
pubmed:articleTitle
Immune response of cows fed polyunsaturated fatty acids under high ambient temperatures.
pubmed:affiliation
Dipartimento PRIME and Istituto per Ricerca e Applicazioni Biotecnologiche per Sicurezza e Valorizzazione dei Prodotti Tipici e di Qualità (BIOAGROMED), Università di Foggia, Via Napoli 25, 71100 Foggia, Italy. m.caroprese@unifg.it
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't