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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
8
|
| pubmed:dateCreated |
1991-12-2
|
| pubmed:abstractText |
Heparin therapy in acute stroke is a controversial issue. It is uncertain, whether heparin has a therapeutic or preventive effect in the early phase of the stroke. From 1984-1989, 1095 patients with acute ischemic stroke were treated, 141 (12.9%) of whom received heparin within 3 days of stroke onset. The mean duration of heparin anticoagulation was 10 days. In 28 cases (20%), heparin was used as antithrombotic agent (25/28 patients suffered a basilar artery occlusion, of whom 22 died). In 113 cases (80%), heparin was used in embolic stroke to prevent recurrence (24% cardioembolic stroke, 54% arterio-arterial embolism, and 22% embolism of unknown etiology). The rate of recurrent stroke in the early phase was 13% with a persistent deficit in 5.3%. The results are comparable with those of other trials reported in the literature. Only 2 patients had an anticoagulation-related haemorrhage with clinical deterioration. Heparin anticoagulation in acute stroke is a low-risk therapy, but its preventive value has not yet been demonstrated.
|
| pubmed:language |
ger
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Aug
|
| pubmed:issn |
0028-2804
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
62
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
477-82
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:1944711-Adult,
pubmed-meshheading:1944711-Aged,
pubmed-meshheading:1944711-Aged, 80 and over,
pubmed-meshheading:1944711-Brain Ischemia,
pubmed-meshheading:1944711-Cerebral Hemorrhage,
pubmed-meshheading:1944711-Cerebral Infarction,
pubmed-meshheading:1944711-Drug Administration Schedule,
pubmed-meshheading:1944711-Female,
pubmed-meshheading:1944711-Heparin,
pubmed-meshheading:1944711-Humans,
pubmed-meshheading:1944711-Infusions, Intravenous,
pubmed-meshheading:1944711-Intracranial Embolism and Thrombosis,
pubmed-meshheading:1944711-Ischemic Attack, Transient,
pubmed-meshheading:1944711-Male,
pubmed-meshheading:1944711-Middle Aged,
pubmed-meshheading:1944711-Partial Thromboplastin Time,
pubmed-meshheading:1944711-Recurrence,
pubmed-meshheading:1944711-Retrospective Studies,
pubmed-meshheading:1944711-Tomography, X-Ray Computed
|
| pubmed:year |
1991
|
| pubmed:articleTitle |
[Heparin therapy in embolic cerebral infarct. A retrospective study].
|
| pubmed:affiliation |
Neurologische Klinik, Klinikums Minden.
|
| pubmed:publicationType |
Journal Article,
English Abstract
|