Linked Life Data

1944469

Source:http://linkedlifedata.com/resource/pubmed/id/1944469

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
24
pubmed:dateCreated
1991-12-17
pubmed:abstractText
The McCune-Albright syndrome is a sporadic disease characterized by polyostotic fibrous dysplasia, café au lait spots, sexual precocity, and hyperfunction of multiple endocrine glands. These manifestations may be explained by a somatic mutation in affected tissues that results in activation of the signal-transduction pathway generating cyclic AMP (cAMP). We analyzed DNA from tissues of patients with the McCune-Albright syndrome for the presence of activating mutations of the gene for the alpha subunit of the G protein (Gs alpha) that stimulates cAMP formation.
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0028-4793
pubmed:author
pubmed:issnType
Print
pubmed:day
12
pubmed:volume
325
pubmed:geneSymbol
Gsalpha
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1688-95
pubmed:dateRevised
2010-3-24
pubmed:meshHeading
pubmed:year
1991
pubmed:articleTitle
Activating mutations of the stimulatory G protein in the McCune-Albright syndrome.
pubmed:affiliation
Molecular Pathophysiology Branch, National Institute of Diabetes and Digestive and Kidney Diseases, NIH, Bethesda, MD 20892.
pubmed:publicationType
Journal Article, Case Reports