Source:http://linkedlifedata.com/resource/pubmed/id/19439264
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
9
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pubmed:dateCreated |
2009-5-14
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pubmed:abstractText |
The lateral line organ is a mechanosensory organ of fish and amphibians that detects changes in water flow. The lateral line organ of zebrafish has been used as a model for cell polarity and collective cell migration as well as hair cell loss and regeneration. A combination of genetic tools and live imaging has allowed dissection of signaling pathways that regulate these processes. Here, we summarize recent findings on the roles of the FGF, Wnt/beta-catenin, and Notch pathways in the initial formation of the posterior lateral line primordium, as well as during organ patterning, migration, cell fate specification and hair cell regeneration.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
1879-0445
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:day |
12
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pubmed:volume |
19
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
R381-6
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pubmed:meshHeading |
pubmed-meshheading:19439264-Animals,
pubmed-meshheading:19439264-Cell Differentiation,
pubmed-meshheading:19439264-Cell Movement,
pubmed-meshheading:19439264-Fibroblast Growth Factors,
pubmed-meshheading:19439264-Lateral Line System,
pubmed-meshheading:19439264-Morphogenesis,
pubmed-meshheading:19439264-Receptors, Notch,
pubmed-meshheading:19439264-Signal Transduction,
pubmed-meshheading:19439264-Wnt Proteins,
pubmed-meshheading:19439264-Zebrafish,
pubmed-meshheading:19439264-beta Catenin
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pubmed:year |
2009
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pubmed:articleTitle |
Signaling pathways regulating zebrafish lateral line development.
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pubmed:affiliation |
University of Washington, Box 357420, Seattle, WA 98195-7420, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.,
Review,
Research Support, N.I.H., Extramural
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