Source:http://linkedlifedata.com/resource/pubmed/id/19438253
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
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pubmed:dateCreated |
2009-6-26
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pubmed:abstractText |
Ten new ingol lathyrane-type diterpenes (1-10) and two known ingenol derivatives (11 and 12) were isolated from the aerial parts of Euphorbia royleana. The structures of 1-10 were elucidated on the basis of spectroscopic methods including 2D NMR analysis, and the structure of compound 1 was confirmed by single-crystal X-ray crystallography. Antiangiogenic effects of all compounds except for 5 were tested using a zebrafish model, with compounds 11 and 12 being active in this bioassay.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
1520-6025
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:volume |
72
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1001-5
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pubmed:meshHeading |
pubmed-meshheading:19438253-Angiogenesis Inhibitors,
pubmed-meshheading:19438253-Animals,
pubmed-meshheading:19438253-Crystallography, X-Ray,
pubmed-meshheading:19438253-Disease Models, Animal,
pubmed-meshheading:19438253-Diterpenes,
pubmed-meshheading:19438253-Euphorbia,
pubmed-meshheading:19438253-Molecular Conformation,
pubmed-meshheading:19438253-Molecular Structure,
pubmed-meshheading:19438253-Nuclear Magnetic Resonance, Biomolecular,
pubmed-meshheading:19438253-Zebrafish
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pubmed:year |
2009
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pubmed:articleTitle |
Ingol and ingenol diterpenes from the aerial parts of Euphorbia royleana and their antiangiogenic activities.
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pubmed:affiliation |
Laboratory of Ethnobotany, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming Yunnan, People's Republic of China.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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