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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
2009-5-13
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pubmed:abstractText |
Environmental enrichment (EE) fosters attachment behavior through its effect on brain oxytocin levels in the hippocampus and other brain regions, which in turn modulate the hypothalamic-pituitary axis (HPA). Social isolation and other stressors negatively impact physical healing through their effect on the HPA. Therefore, we reasoned that: 1) provision of a rat EE (nest building with Nestlets) would improve wound healing in rats undergoing stress due to isolation rearing and 2) that oxytocin would have a similar beneficial effect on wound healing.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1932-6203
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pubmed:author |
pubmed-author:BensonHerbertH,
pubmed-author:BerdichevskyYevgenyY,
pubmed-author:BerthiaumeFrancoisF,
pubmed-author:CasaliMonicaM,
pubmed-author:FricchioneGregory LGL,
pubmed-author:FricchioneJonathanJ,
pubmed-author:HogeElizabeth AEA,
pubmed-author:LevineJohn BJB,
pubmed-author:RauchScott LSL,
pubmed-author:VitaloAntoniaA,
pubmed-author:YarmushMartin LML
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pubmed:issnType |
Electronic
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pubmed:volume |
4
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
e5523
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:19436750-Animals,
pubmed-meshheading:19436750-Behavior, Animal,
pubmed-meshheading:19436750-Hypothalamo-Hypophyseal System,
pubmed-meshheading:19436750-Male,
pubmed-meshheading:19436750-Oxytocin,
pubmed-meshheading:19436750-Rats,
pubmed-meshheading:19436750-Rats, Sprague-Dawley,
pubmed-meshheading:19436750-Social Environment,
pubmed-meshheading:19436750-Social Isolation,
pubmed-meshheading:19436750-Stress, Psychological,
pubmed-meshheading:19436750-Wound Healing
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pubmed:year |
2009
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pubmed:articleTitle |
Nest making and oxytocin comparably promote wound healing in isolation reared rats.
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pubmed:affiliation |
Department of Surgery, Massachusetts General Hospital, Boston, Massachusetts, USA.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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