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pubmed:abstractText |
The insulin analogs lispro, aspart, and glulisine are the only commercially available rapid-acting insulins to treat diabetes. We review the evidence for treating hyperglycemia, using insulin, and specifically using rapid-acting analogs in diabetic individuals, on the prevention of vascular events. We review the beneficial effects of insulin on the vascular system, which include vasodilation and anti-inflammatory actions. The effects of treating hyperglycemia and intensive blood glucose control on vascular outcomes are reviewed.
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pubmed:affiliation |
Department of Medicine, Division of Endocrinology, University of Texas, Southwestern Medical Center, Dallas, TX 75390-8858, USA.
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