|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0009498,
umls-concept:C0011155,
umls-concept:C0025294,
umls-concept:C0026882,
umls-concept:C0030705,
umls-concept:C0034897,
umls-concept:C0205314,
umls-concept:C0332281,
umls-concept:C0449432,
umls-concept:C0679622,
umls-concept:C1179435,
umls-concept:C1524073,
umls-concept:C1548799,
umls-concept:C1705248
|
|
pubmed:issue |
5
|
|
pubmed:dateCreated |
2009-8-20
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|
pubmed:abstractText |
Complement component C8 is one of the five terminal complement components required for the formation of the membrane attack complex. Complete absence of C8 results in increased susceptibility to gram-negative bacteria such as Neisseria species.
|
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pubmed:grant |
|
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pubmed:language |
eng
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|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Sep
|
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pubmed:issn |
1573-2592
|
|
pubmed:author |
|
|
pubmed:issnType |
Electronic
|
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pubmed:volume |
29
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
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pubmed:pagination |
691-5
|
|
pubmed:meshHeading |
pubmed-meshheading:19434484-Adolescent,
pubmed-meshheading:19434484-Antibiotic Prophylaxis,
pubmed-meshheading:19434484-Codon, Nonsense,
pubmed-meshheading:19434484-Complement C8,
pubmed-meshheading:19434484-Cytotoxicity, Immunologic,
pubmed-meshheading:19434484-DNA Mutational Analysis,
pubmed-meshheading:19434484-Genetic Predisposition to Disease,
pubmed-meshheading:19434484-Haemophilus Vaccines,
pubmed-meshheading:19434484-Humans,
pubmed-meshheading:19434484-Immunologic Deficiency Syndromes,
pubmed-meshheading:19434484-Immunotherapy,
pubmed-meshheading:19434484-Male,
pubmed-meshheading:19434484-Meningitis, Meningococcal,
pubmed-meshheading:19434484-Penicillins,
pubmed-meshheading:19434484-Pneumococcal Vaccines,
pubmed-meshheading:19434484-Recurrence,
pubmed-meshheading:19434484-Sepsis
|
|
pubmed:year |
2009
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|
pubmed:articleTitle |
A novel mutation in a patient with a deficiency of the eighth component of complement associated with recurrent meningococcal meningitis.
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|
pubmed:affiliation |
Department of Clinical Immunology, Nuffield Department of Medicine, University of Oxford and Oxford Radcliffe Hospitals, John Radcliffe Hospital, Oxford OX3 9DU, UK.
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pubmed:publicationType |
Journal Article,
Case Reports,
Research Support, Non-U.S. Gov't
|
