Linked Life Data

19433343

Source:http://linkedlifedata.com/resource/pubmed/id/19433343

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
10
pubmed:dateCreated
2009-8-3
pubmed:abstractText
A series of 3,9-dihydro-9-oxo-5H-imidazo[1,2-A]purine nucleosides (tricylic nucleosides) were synthesized from 9-[4-alpha-(hydroxymethyl)cyclopent-2-ene-1-alpha-yl]guanine (CBV) 5, (-)-beta-D-(2R,4R)-1,3-dioxolane-guanosine (DXG) 6, 3'-azido-3'-deoxy-guanosine (AZG) 7, and 2'-C-methylguanosine 8. Their in vitro activity against HIV and HCV was evaluated and correlated to their ability to degrade to their purine counterpart.
pubmed:grant
http://linkedlifedata.com/resource/pubmed/grant/5P30-AI-50409, http://linkedlifedata.com/resource/pubmed/grant/5R01-AI-071846, http://linkedlifedata.com/resource/pubmed/grant/5R37-AI-041980, http://linkedlifedata.com/resource/pubmed/grant/P30 AI050409-109005, http://linkedlifedata.com/resource/pubmed/grant/R01 AI041980-03, http://linkedlifedata.com/resource/pubmed/grant/R01 AI071846-01A1, http://linkedlifedata.com/resource/pubmed/grant/R01 AI071846-02, http://linkedlifedata.com/resource/pubmed/grant/R01 AI071846-03, http://linkedlifedata.com/resource/pubmed/grant/R37 AI041980-04, http://linkedlifedata.com/resource/pubmed/grant/R37 AI041980-05, http://linkedlifedata.com/resource/pubmed/grant/R37 AI041980-05S1, http://linkedlifedata.com/resource/pubmed/grant/R37 AI041980-06, http://linkedlifedata.com/resource/pubmed/grant/R37 AI041980-07, http://linkedlifedata.com/resource/pubmed/grant/R37 AI041980-08, http://linkedlifedata.com/resource/pubmed/grant/R37 AI041980-08S1, http://linkedlifedata.com/resource/pubmed/grant/R37 AI041980-09, http://linkedlifedata.com/resource/pubmed/grant/R37 AI041980-10, http://linkedlifedata.com/resource/pubmed/grant/R37 AI041980-11, http://linkedlifedata.com/resource/pubmed/grant/R37 AI041980-12
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
1768-3254
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
44
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
3845-51
pubmed:dateRevised
2011-9-22
pubmed:meshHeading
pubmed:year
2009
pubmed:articleTitle
Synthesis, antiviral activity, and stability of nucleoside analogs containing tricyclic bases.
pubmed:affiliation
Department of Pediatrics, Center for AIDS Research, Veterans Affairs Medical Center, Laboratory of Biochemical Pharmacology, Emory University School of Medicine, Atlanta, GA 30033, USA.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, Non-P.H.S., Research Support, N.I.H., Extramural