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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
1991-11-27
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pubmed:abstractText |
Twenty consecutive patients with metastatic malignant melanoma were treated with a combination of 24 hours continuous infusion of dacarbazine (250 mg/m2) and cisplatin (20 mg/m2) for 5 days every 3 weeks. One patient (5%) achieved a complete response (CR) and 3 patients (15%) obtained a partial response (PR) with an overall response rate of 20%. Minimal response was observed in 5 other patients (25%). Complete response duration was 8 months. Median response duration of partial responders was 7 months. Median survival of all responders (CR+PR) was 8.5 months. Toxicity was mild to moderate.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0022-4790
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
48
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
199-201
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pubmed:dateRevised |
2006-4-24
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pubmed:meshHeading |
pubmed-meshheading:1943117-Adult,
pubmed-meshheading:1943117-Aged,
pubmed-meshheading:1943117-Antineoplastic Combined Chemotherapy Protocols,
pubmed-meshheading:1943117-Cisplatin,
pubmed-meshheading:1943117-Dacarbazine,
pubmed-meshheading:1943117-Drug Administration Schedule,
pubmed-meshheading:1943117-Female,
pubmed-meshheading:1943117-Humans,
pubmed-meshheading:1943117-Infusions, Intravenous,
pubmed-meshheading:1943117-Male,
pubmed-meshheading:1943117-Melanoma,
pubmed-meshheading:1943117-Middle Aged,
pubmed-meshheading:1943117-Pilot Projects,
pubmed-meshheading:1943117-Remission Induction,
pubmed-meshheading:1943117-Survival Analysis
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pubmed:year |
1991
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pubmed:articleTitle |
Treatment of metastatic malignant melanoma with 24 hours continuous venous infusion of dacarbazine and cisplatin.
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pubmed:affiliation |
Medical Oncology Section, University of Ankara Medical School, Turkey.
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pubmed:publicationType |
Journal Article
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