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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1-2
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pubmed:dateCreated |
2009-8-5
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pubmed:abstractText |
A mydriatic pupil has been infrequently reported as a manifestation of giant cell arteritis. We report a patient with acute, evolving pupil dilation who was diagnosed with biopsy-proven giant cell arteritis. We document the time course for the development of pupillary near-light dissociation and denervation hypersensitivity. We discuss the possible mechanisms leading to mydriasis, including 1) parasympathetic dysfunction due to ischemia of the ciliary ganglion and post-ganglionic parasympathetic fibers and 2) direct iris ischemia. Repeated episodes of pupil dilation in this patient suggested ongoing microvascular insufficiency.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
1878-5883
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:day |
15
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pubmed:volume |
284
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
196-7
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pubmed:meshHeading |
pubmed-meshheading:19427648-Aged, 80 and over,
pubmed-meshheading:19427648-Amaurosis Fugax,
pubmed-meshheading:19427648-Anisocoria,
pubmed-meshheading:19427648-Dermatomyositis,
pubmed-meshheading:19427648-Diabetes Complications,
pubmed-meshheading:19427648-Ganglia, Parasympathetic,
pubmed-meshheading:19427648-Giant Cell Arteritis,
pubmed-meshheading:19427648-Humans,
pubmed-meshheading:19427648-Hyperlipidemias,
pubmed-meshheading:19427648-Iris,
pubmed-meshheading:19427648-Ischemia,
pubmed-meshheading:19427648-Male,
pubmed-meshheading:19427648-Microcirculation,
pubmed-meshheading:19427648-Parasympathetic Fibers, Postganglionic,
pubmed-meshheading:19427648-Pilocarpine,
pubmed-meshheading:19427648-Polymyalgia Rheumatica,
pubmed-meshheading:19427648-Recurrence,
pubmed-meshheading:19427648-Tonic Pupil
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pubmed:year |
2009
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pubmed:articleTitle |
Mydriatic pupil in giant cell arteritis.
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pubmed:affiliation |
Division of Neuro-ophthalmology, Department of Neurology, Hospital of the University of Pennsylvania, United States. sashank.prasad@uphs.upenn.edu
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pubmed:publicationType |
Journal Article,
Case Reports
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