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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2009-5-8
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pubmed:abstractText |
Chlamydia spp. are important pathogens of humans and animals that cause a wide range of acute and chronic infections. A persistence model has been developed in which Chlamydia spp. do not complete their developmental cycle, have significantly reduced infectivity for new host cells, and exhibit abnormal inclusion and reticulate body morphology. This study was performed to compare the interferon-gamma (IFN-gamma) induction and iron-limitation models of persistence for Chlamydia spp. to investigate the common and unique transcriptional pathways involved.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
1995-9133
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
42
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
27-37
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pubmed:meshHeading |
pubmed-meshheading:19424556-Bacterial Outer Membrane Proteins,
pubmed-meshheading:19424556-Bacterial Proteins,
pubmed-meshheading:19424556-Cell Line, Tumor,
pubmed-meshheading:19424556-Chlamydophila pneumoniae,
pubmed-meshheading:19424556-Gene Expression Regulation, Bacterial,
pubmed-meshheading:19424556-Heat-Shock Proteins,
pubmed-meshheading:19424556-Humans,
pubmed-meshheading:19424556-Interferon-gamma,
pubmed-meshheading:19424556-Iron,
pubmed-meshheading:19424556-Models, Biological,
pubmed-meshheading:19424556-Polymerase Chain Reaction,
pubmed-meshheading:19424556-Reproducibility of Results
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pubmed:year |
2009
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pubmed:articleTitle |
Differential transcriptional responses between the interferon-gamma-induction and iron-limitation models of persistence for Chlamydia pneumoniae.
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pubmed:affiliation |
School of Life Sciences, Queensland University of Technology, Institute of Health and Biomedical Innovation, Brisbane, Australia. p.timms@qut.edu.au
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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