19424056

Source:http://linkedlifedata.com/resource/pubmed/id/19424056

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0019704, umls-concept:C0282554, umls-concept:C0597357, umls-concept:C1332823, umls-concept:C1511790, umls-concept:C1514562, umls-concept:C2737269
pubmed:issue	10
pubmed:dateCreated	2009-6-10
pubmed:abstractText	Identification of low-frequency variants is of clinical importance in the identification of preexisting drug resistance. Using 'ultra-deep' sequencing, we address the detection of potential resistance to the chemokine (C-C motif) receptor 5 (CCR5) antagonist, maraviroc, due to the pretreatment presence of low levels of chemokine (CXC motif) receptor 4 (CXCR4)-using virus.
pubmed:grant	http://linkedlifedata.com/resource/pubmed/grant/, http://linkedlifedata.com/resource/pubmed/grant/083798/Z/07/Z, http://linkedlifedata.com/resource/pubmed/grant/BB/A517677/1
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pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/8710219
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/CXCR4 protein, human, http://linkedlifedata.com/resource/pubmed/chemical/Cyclohexanes, http://linkedlifedata.com/resource/pubmed/chemical/DNA, Viral, http://linkedlifedata.com/resource/pubmed/chemical/HIV Fusion Inhibitors, http://linkedlifedata.com/resource/pubmed/chemical/Receptors, CXCR4, http://linkedlifedata.com/resource/pubmed/chemical/Triazoles, http://linkedlifedata.com/resource/pubmed/chemical/maraviroc
pubmed:status	MEDLINE
pubmed:month	Jun
pubmed:issn	1473-5571
pubmed:author	pubmed-author:ArcherJohnJ, pubmed-author:BravermanMichael SMS, pubmed-author:DesanyBrianB, pubmed-author:HarriganP RichardPR, pubmed-author:JamesIanI, pubmed-author:LewisMarilynM, pubmed-author:RobertsonDavid LDL, pubmed-author:TaillonBruce EBE
pubmed:issnType	Electronic
pubmed:day	19
pubmed:volume	23
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	1209-18
pubmed:dateRevised	2010-9-24
pubmed:meshHeading	pubmed-meshheading:19424056-Cyclohexanes, pubmed-meshheading:19424056-DNA, Viral, pubmed-meshheading:19424056-Drug Resistance, Viral, pubmed-meshheading:19424056-Evolution, Molecular, pubmed-meshheading:19424056-HIV Fusion Inhibitors, pubmed-meshheading:19424056-HIV Infections, pubmed-meshheading:19424056-HIV-1, pubmed-meshheading:19424056-Humans, pubmed-meshheading:19424056-Phenotype, pubmed-meshheading:19424056-Phylogeny, pubmed-meshheading:19424056-Receptors, CXCR4, pubmed-meshheading:19424056-Sequence Alignment, pubmed-meshheading:19424056-Sequence Analysis, DNA, pubmed-meshheading:19424056-Triazoles
pubmed:year	2009
pubmed:articleTitle	Detection of low-frequency pretherapy chemokine (CXC motif) receptor 4 (CXCR4)-using HIV-1 with ultra-deep pyrosequencing.
pubmed:affiliation	University of Manchester, UK.
pubmed:publicationType	Journal Article, Research Support, Non-U.S. Gov't