Linked Life Data

19423341

Source:http://linkedlifedata.com/resource/pubmed/id/19423341

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
12
pubmed:dateCreated
2009-5-29
pubmed:abstractText
A series of aromatic acetic acid compounds were designed and synthesized on the basis of Non-steroidal anti-inflammatory drugs indomethacin and diclofenac. Compounds 5a, 7a, 5h, 7h and 17 could strongly promote insulin-regulated differentiation of 3T3-L1 cells in vitro. They acted as full or partial PPARgamma agonist, or improved insulin resistance through non-PPARgamma pathway.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
1464-3405
pubmed:author
pubmed:issnType
Electronic
pubmed:day
15
pubmed:volume
19
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
3324-7
pubmed:dateRevised
2011-11-17
pubmed:meshHeading
pubmed:year
2009
pubmed:articleTitle
Design, synthesis and insulin-sensitizing activity of indomethacin and diclofenac derivatives.
pubmed:affiliation
School of Pharmacy, Guiyang Medical College, Guiyang 550004, China.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't