19423156

Source:http://linkedlifedata.com/resource/pubmed/id/19423156

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0002092, umls-concept:C0003315, umls-concept:C0017337, umls-concept:C0042210, umls-concept:C0086418, umls-concept:C0123242, umls-concept:C0599894, umls-concept:C1710360
pubmed:issue	1
pubmed:dateCreated	2009-6-29
pubmed:abstractText	Treatment of IgE-mediated food allergy with standard protein-based allergen immunotherapy has proved both unsuccessful and hazardous. Allergen gene vaccination represents a promising alternative, but difficulties in gene targeting and expression in antigen-presenting cells represent a major limitation for efficient gene vaccination.
pubmed:grant	http://linkedlifedata.com/resource/pubmed/grant/AI 15251, http://linkedlifedata.com/resource/pubmed/grant/R01 AI015251-28
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pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/1275002
pubmed:citationSubset	AIM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Immunoglobulin E, http://linkedlifedata.com/resource/pubmed/chemical/Polylysine, http://linkedlifedata.com/resource/pubmed/chemical/Receptors, IgE, http://linkedlifedata.com/resource/pubmed/chemical/Recombinant Proteins, http://linkedlifedata.com/resource/pubmed/chemical/Vaccines, DNA
pubmed:status	MEDLINE
pubmed:month	Jul
pubmed:issn	1097-6825
pubmed:author	pubmed-author:BehneckeAnneA, pubmed-author:ChenLingL, pubmed-author:FuY PYP, pubmed-author:SaxonAndrewA, pubmed-author:ZhangKeK
pubmed:issnType	Electronic
pubmed:volume	124
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	108-13
pubmed:dateRevised	2010-9-24
pubmed:meshHeading	pubmed-meshheading:19423156-Animals, pubmed-meshheading:19423156-Antigen-Presenting Cells, pubmed-meshheading:19423156-Blotting, Western, pubmed-meshheading:19423156-CHO Cells, pubmed-meshheading:19423156-Cricetinae, pubmed-meshheading:19423156-Cricetulus, pubmed-meshheading:19423156-Desensitization, Immunologic, pubmed-meshheading:19423156-Drug Delivery Systems, pubmed-meshheading:19423156-Humans, pubmed-meshheading:19423156-Immunoglobulin E, pubmed-meshheading:19423156-Mice, pubmed-meshheading:19423156-Polylysine, pubmed-meshheading:19423156-Receptors, IgE, pubmed-meshheading:19423156-Recombinant Proteins, pubmed-meshheading:19423156-Vaccines, DNA
pubmed:year	2009
pubmed:articleTitle	IgE-mediated allergen gene vaccine platform targeting human antigen-presenting cells through the high-affinity IgE receptor.
pubmed:affiliation	Hart and Louise Lyon Immunology Laboratory, Section of Clinical Immunology/Allergy, Division of Pulmonary, Critical Care and Clinical Immunology/Allergy, Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA.
pubmed:publicationType	Journal Article, Research Support, Non-U.S. Gov't, Research Support, N.I.H., Extramural