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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
9
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pubmed:dateCreated |
2009-9-1
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pubmed:abstractText |
Clinical presentation at diagnosis and disease course of Crohn's disease (CD) are heterogeneous and variable over time. Early introduction of immunomodulators and/or biologicals might be justified in patients at risk for disease progression, so it is important to identify these patients as soon as possible. We examined the influence of recently discovered CD-associated susceptibility loci on changes in disease behavior and evaluated whether a genetic risk model for disease progression could be generated.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
1542-7714
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
7
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
972-980.e2
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:19422935-Adolescent,
pubmed-meshheading:19422935-Adult,
pubmed-meshheading:19422935-Crohn Disease,
pubmed-meshheading:19422935-Cyclin-Dependent Kinase 5,
pubmed-meshheading:19422935-DNA Fingerprinting,
pubmed-meshheading:19422935-Disease Progression,
pubmed-meshheading:19422935-Disease Susceptibility,
pubmed-meshheading:19422935-Female,
pubmed-meshheading:19422935-Gene Frequency,
pubmed-meshheading:19422935-Genetic Predisposition to Disease,
pubmed-meshheading:19422935-Genetic Testing,
pubmed-meshheading:19422935-Humans,
pubmed-meshheading:19422935-Kaplan-Meier Estimate,
pubmed-meshheading:19422935-Logistic Models,
pubmed-meshheading:19422935-Male,
pubmed-meshheading:19422935-Models, Genetic,
pubmed-meshheading:19422935-Nod2 Signaling Adaptor Protein,
pubmed-meshheading:19422935-Polymorphism, Single Nucleotide,
pubmed-meshheading:19422935-Predictive Value of Tests,
pubmed-meshheading:19422935-Rectal Fistula,
pubmed-meshheading:19422935-Sex Factors,
pubmed-meshheading:19422935-Young Adult
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pubmed:year |
2009
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pubmed:articleTitle |
Genetic risk profiling and prediction of disease course in Crohn's disease patients.
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pubmed:affiliation |
Department of Medicine, Gastroenterology Section, Catholic University of Leuven, Leuven, Belgium. liesbet.henckaerts@uzleuven.be
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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