Source:http://linkedlifedata.com/resource/pubmed/id/19416084
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
2009-5-6
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pubmed:abstractText |
Antimicrobial drugs exhibit different characteristics in their correlation between antimicrobial drug concentrations and effects on microorganisms. These correlations have been studied using different approaches including in vitro analyses with constant and fluctuating concentrations and in vivo analyses involving animals and humans. Mathematical analysis includes correlation of pharmacokinetic-pharmacodynamic (PK-PD) indices to an outcome parameter. Further insight can be gained by mechanism-based modelling of antimicrobial drug effects.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
1744-7607
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:volume |
5
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
475-87
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pubmed:dateRevised |
2009-11-16
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pubmed:meshHeading |
pubmed-meshheading:19416084-Animals,
pubmed-meshheading:19416084-Anti-Bacterial Agents,
pubmed-meshheading:19416084-Anti-Infective Agents,
pubmed-meshheading:19416084-Bacteria,
pubmed-meshheading:19416084-Dose-Response Relationship, Drug,
pubmed-meshheading:19416084-Drug Resistance, Bacterial,
pubmed-meshheading:19416084-Humans,
pubmed-meshheading:19416084-Models, Biological
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pubmed:year |
2009
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pubmed:articleTitle |
Pharmacokinetics and pharmacodynamics of antimicrobial drugs.
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pubmed:affiliation |
Department of Internal Medicine VI, Clinical Pharmacology and Pharmacoepidemiology, University Hospital Heidelberg, Heidelberg, Germany.
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pubmed:publicationType |
Journal Article,
Review
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