|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
1-2
|
|
pubmed:dateCreated |
2009-6-9
|
|
pubmed:abstractText |
Periodontitis is a chronic inflammatory disease that results in gingival inflammation and periodontal tissue destruction and is accompanied by alveolar bone resorption and eventual tooth loss. We examined the effect of 15-deoxy-Delta(12,14)-prostaglandin J(2) (15d-PGJ(2)) on periodontitis by inhibiting the production of interleukin-6 (IL-6).
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Jul
|
|
pubmed:issn |
1879-0631
|
|
pubmed:author |
|
|
pubmed:issnType |
Electronic
|
|
pubmed:day |
3
|
|
pubmed:volume |
85
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
46-53
|
|
pubmed:dateRevised |
2009-11-19
|
|
pubmed:meshHeading |
pubmed-meshheading:19409914-3T3 Cells,
pubmed-meshheading:19409914-Animals,
pubmed-meshheading:19409914-Blotting, Western,
pubmed-meshheading:19409914-Cell Survival,
pubmed-meshheading:19409914-Electrophoretic Mobility Shift Assay,
pubmed-meshheading:19409914-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:19409914-I-kappa B Proteins,
pubmed-meshheading:19409914-Interleukin-6,
pubmed-meshheading:19409914-Lipopolysaccharides,
pubmed-meshheading:19409914-Mice,
pubmed-meshheading:19409914-Microscopy, Confocal,
pubmed-meshheading:19409914-NF-kappa B,
pubmed-meshheading:19409914-Oncogene Protein v-akt,
pubmed-meshheading:19409914-Osteoblasts,
pubmed-meshheading:19409914-PPAR gamma,
pubmed-meshheading:19409914-Prostaglandin D2,
pubmed-meshheading:19409914-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:19409914-Translocation, Genetic
|
|
pubmed:year |
2009
|
|
pubmed:articleTitle |
The 15-deoxy-Delta12,14-prostaglandin J2 inhibits LPS-stimulated AKT and NF-kappaB activation and suppresses interleukin-6 in osteoblast-like cells MC3T3E-1.
|
|
pubmed:affiliation |
Department of Marine Life Science, Chosun University, Gwangju, Republic of Korea.
|
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
