Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
8
pubmed:dateCreated
2009-7-14
pubmed:abstractText
Most recent studies on the effectiveness of cerebral revascularization have focused on the treatment of atherosclerotic internal carotid artery occlusive disease. The goal of the present study was to assess neurological function in 11 severe atherosclerotic middle cerebral artery (MCA) disease patients with transient ischemic attacks (TIAs) and hemodynamic compromise and determine the efficacy of superficial temporal artery-middle cerebral artery (STA-MCA) bypass. There were eight patients with MCA occlusion and three with severe MCA stenosis. After the bypass procedure, all 11 patients experienced reduction in TIAs and no stroke during a mean follow-up of 34.36 months. Surgical revascularization increased regional cerebral blood flow (mL/100g/min) from a mean of (+/- standard deviation) 25.9+/-7.39 preoperatively to 32.3+/-7.72 postoperatively, and improved regional cerebrovascular reactivity from -6.42%+/-14.61% to 30.14%+/-23.93% (p = 0.014) in the eight patients with atherosclerotic MCA occlusion. Our findings demonstrated the benefit of STA-MCA bypass for patients with medically refractory and symptomatic atherosclerotic MCA occlusion with hemodynamic compromise.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0967-5868
pubmed:author
pubmed:issnType
Print
pubmed:volume
16
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1013-7
pubmed:meshHeading
pubmed-meshheading:19409794-Aged, pubmed-meshheading:19409794-Brain Ischemia, pubmed-meshheading:19409794-Cerebral Angiography, pubmed-meshheading:19409794-Cerebrovascular Circulation, pubmed-meshheading:19409794-Constriction, Pathologic, pubmed-meshheading:19409794-Female, pubmed-meshheading:19409794-Humans, pubmed-meshheading:19409794-Infarction, Middle Cerebral Artery, pubmed-meshheading:19409794-Intracranial Arteriosclerosis, pubmed-meshheading:19409794-Ischemic Attack, Transient, pubmed-meshheading:19409794-Male, pubmed-meshheading:19409794-Middle Aged, pubmed-meshheading:19409794-Middle Cerebral Artery, pubmed-meshheading:19409794-Perfusion Imaging, pubmed-meshheading:19409794-Severity of Illness Index, pubmed-meshheading:19409794-Temporal Arteries, pubmed-meshheading:19409794-Tomography, X-Ray Computed, pubmed-meshheading:19409794-Treatment Outcome
pubmed:year
2009
pubmed:articleTitle
Superficial temporal artery-middle cerebral artery bypass for ischemic atherosclerotic middle cerebral artery disease.
pubmed:affiliation
Department of Neurosurgery, Buddhist Tzu Chi General Hospital/Tzu Chi University, Hualien, Taiwan.
pubmed:publicationType
Journal Article