Source:http://linkedlifedata.com/resource/pubmed/id/19405859
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
2009-7-2
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pubmed:abstractText |
BACKGROUND DATA AND OBJECTIVE: Mesenchymal stem cells (MSCs) are multipotent cells present in adult bone marrow that replicate as undifferentiated cells and can differentiate to lineages of mesenchymal tissues. Homeostatic control of bone remodeling maintains bone mass by ensuring that bone resorption and bone formation occur sequentially and in a balanced manner. As most homeostatic functions occur in a circadian manner, a circadian clock could control bone mass. Here we show that laser irradiation can direct the extracellular calcification of mouse MSCs by altering the intracellular localization of the circadian rhythm protein cryptochrome 1 (CRY1).
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
1557-8550
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:volume |
27
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
493-8
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pubmed:dateRevised |
2011-1-11
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pubmed:meshHeading |
pubmed-meshheading:19405859-Animals,
pubmed-meshheading:19405859-Calcification, Physiologic,
pubmed-meshheading:19405859-Cells, Cultured,
pubmed-meshheading:19405859-Circadian Rhythm,
pubmed-meshheading:19405859-Cryptochromes,
pubmed-meshheading:19405859-Flavoproteins,
pubmed-meshheading:19405859-Lasers,
pubmed-meshheading:19405859-Male,
pubmed-meshheading:19405859-Mesenchymal Stem Cells,
pubmed-meshheading:19405859-Mice,
pubmed-meshheading:19405859-Mice, Inbred BALB C,
pubmed-meshheading:19405859-Osteogenesis,
pubmed-meshheading:19405859-Polymerase Chain Reaction
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pubmed:year |
2009
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pubmed:articleTitle |
Blue laser irradiation enhances extracellular calcification of primary mesenchymal stem cells.
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pubmed:affiliation |
Frontier Research Base for Global Young Researchers, Frontier Research Center, Graduate School of Engineering, Osaka University, Osaka, Japan. kushibiki@see.eng.osaka-u.ac.jp
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pubmed:publicationType |
Journal Article
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