Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2009-7-2
pubmed:abstractText
BACKGROUND DATA AND OBJECTIVE: Mesenchymal stem cells (MSCs) are multipotent cells present in adult bone marrow that replicate as undifferentiated cells and can differentiate to lineages of mesenchymal tissues. Homeostatic control of bone remodeling maintains bone mass by ensuring that bone resorption and bone formation occur sequentially and in a balanced manner. As most homeostatic functions occur in a circadian manner, a circadian clock could control bone mass. Here we show that laser irradiation can direct the extracellular calcification of mouse MSCs by altering the intracellular localization of the circadian rhythm protein cryptochrome 1 (CRY1).
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
1557-8550
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
27
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
493-8
pubmed:dateRevised
2011-1-11
pubmed:meshHeading
pubmed:year
2009
pubmed:articleTitle
Blue laser irradiation enhances extracellular calcification of primary mesenchymal stem cells.
pubmed:affiliation
Frontier Research Base for Global Young Researchers, Frontier Research Center, Graduate School of Engineering, Osaka University, Osaka, Japan. kushibiki@see.eng.osaka-u.ac.jp
pubmed:publicationType
Journal Article