19403565

Source:http://linkedlifedata.com/resource/pubmed/id/19403565

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0014180, umls-concept:C0065088, umls-concept:C0086418, umls-concept:C0087111, umls-concept:C0205263, umls-concept:C0522537, umls-concept:C1326341
pubmed:issue	8
pubmed:dateCreated	2009-7-15
pubmed:abstractText	In mouse endometrium, glycogen synthase kinase-3beta (GSK3beta) is a key enzyme controlling nuclear localization of cyclin D1. We developed a functional model of xenografted human endometrium to test whether similar mechanisms are operative in the human by using Lithium chloride (LiCl), an inhibitor of GSK3beta.
pubmed:grant	http://linkedlifedata.com/resource/pubmed/grant/K24 HD041978, http://linkedlifedata.com/resource/pubmed/grant/NCI R01 89617, http://linkedlifedata.com/resource/pubmed/grant/RR 95261064, http://linkedlifedata.com/resource/pubmed/grant/T32 HD040135
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pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/8701199
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/CCND1 protein, human, http://linkedlifedata.com/resource/pubmed/chemical/Cyclin D1, http://linkedlifedata.com/resource/pubmed/chemical/Estradiol, http://linkedlifedata.com/resource/pubmed/chemical/Glycogen Synthase Kinase 3, http://linkedlifedata.com/resource/pubmed/chemical/Lithium Chloride, http://linkedlifedata.com/resource/pubmed/chemical/glycogen synthase kinase 3 beta
pubmed:status	MEDLINE
pubmed:month	Aug
pubmed:issn	1460-2350
pubmed:author	pubmed-author:PollardJeffrey WJW, pubmed-author:PolotskyAlex JAJ, pubmed-author:SantoroNanetteN, pubmed-author:ZhuLiyinL
pubmed:issnType	Electronic
pubmed:volume	24
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	1960-7
pubmed:dateRevised	2011-11-2
pubmed:meshHeading	pubmed-meshheading:19403565-Animals, pubmed-meshheading:19403565-Cell Proliferation, pubmed-meshheading:19403565-Cyclin D1, pubmed-meshheading:19403565-Endometrium, pubmed-meshheading:19403565-Epithelial Cells, pubmed-meshheading:19403565-Estradiol, pubmed-meshheading:19403565-Female, pubmed-meshheading:19403565-Glycogen Synthase Kinase 3, pubmed-meshheading:19403565-Humans, pubmed-meshheading:19403565-Lithium Chloride, pubmed-meshheading:19403565-Mice, pubmed-meshheading:19403565-Transplantation, Heterologous
pubmed:year	2009
pubmed:articleTitle	Lithium chloride treatment induces epithelial cell proliferation in xenografted human endometrium.
pubmed:affiliation	Department of Obstetrics & Gynecology and Women's Health, Albert Einstein College of Medicine, Bronx, NY, USA.
pubmed:publicationType	Journal Article, Research Support, N.I.H., Extramural